You can actually know position with quite a high amount of certainty according to the Heisenberg uncertainty principle if you don’t know Jack shit about where it’s going. If you could affect it instantaneously then its velocity would be pretty unimportant.

Whether or not it works physically based on real forces is up to the lore as is how it can be used and abused to manipulate gases and liquids. I’ve seen examples where than can but I think that putting a limiter where they can’t is also totally fair. Also a limiter on how many objects can be affected at once is to be expected. These things can make the difference between near godlike status and pretty decent superhero

Ultimately it’s really up to how the power functions as in what specifically allows for the telekinesis. Just calling it magic for example gives you a lot of wiggle room but making it a physical thing based on forces would certainly limit how you can affect things on a quantum level. There’s also the question of what you can affect based on you senses. Do you need to see it or is visualization and knowledge enough?