Well that’s certainly a game changer
Cool now please help me regrow my gums so my teeth don’t fall out.
First help me regrow my jaw so my gums don’t fall out.
gum disease is no joke. It’ll take your gums and jawbone. Wish someone would help us out.
First help me regrow my head so myyahsbdbdjduxhd
Seeing as teething babies cry a lot, I wonder how painful this process will be.
That’s because their teeth are busting through their fleshy gums. Presumably this would be growing out an existing hole.
Dare ya to search “baby teeth skull”.
Have you had your wisdom teeth grow? I figure this would be the same. With mine it wasn’t a particularly pleasant experience, but it wasn’t too bad either - and if it’s the same with that new treatment, I’d be willing to take the pain over the alternative of staying toothless when I grow old.
Are you supposed to be able to feel wisdom teeth growing? Cause when I got mine there wasn’t any pain
I guess that ideally you don’t feel anything at all, but I’ve heard from a few people that there was some itchiness and irritation, which mirrors my experience, so…
Fortunately didn’t get any of that. Just accidentally biting my inner cheeks with them as they grew.
Less painful than looking at yourself every day in the mirror and staring at your with missing teeth…
Crying isn’t always about pain. Babies can’t talk and don’t have the capacity to realize what’s going on. A lot of their crying can simply be chalked up to the frustration of not being able to communicate, not necessarily from pain.
I had some “teething” as my wisdom teeth came in. It’s painful, and causes a fever, but babies have no understanding of why they are in pain, and no way to deal with it. As an adult, it’s not fun, but it’s manageable and much less scary.
If we learn how to regrow teeth, I wonder if we’ll learn how to regrow bones after that.
We’ll be 3D printing bones relatively soon I’m guessing.
Soon we’ll be farming volunteer humans for bone marrow stew. Sign up, have several bones removed—femur, tibia, you name it—and cracked open for that sweet juicy marrow. Then a steady supply of bone growing pills to start the process all over again.
This is basically the plot to The Marrow Thieves by Cherie Dimaline, minus the volunteering portion
Let’s be honest, once you get the taste for marrow stew the no volunteering part is merely an obstacle.
Super excited for this. One of my adult teeth just never grew in. I tried to get an implant, but the lack of tooth also resulted in too little bone there to support the implant. I’m hopeful this would eventually allow me to have a real tooth there instead of my very fragile bridge.
This is for congenital lack of teeth. not for people who have had their teeth removed.
Not yet, but it could potentially lead to further innovations in that regard.
That appears to be the current goal, but it still looks like the phase-1 will be on healthy adults which is pretty creepy to imagine!
deleted by creator
Not really. The research papers mention an interaction between an antibody and a gene that controls tooth growth in both humans and mice. If that gene is supressed, there is no tooth growth.
However, every tooth you can ever grow, or at least the embryonal tissue for it, is already present at birth. There is no way to get more, and activating this gene would not give you additional tissue to develop into new teeth.
So are they only looking at safety and toxicity in this trial, and not expecting to see additional tooth growth?
So…. Anybody else feel this is……
I dunno… weird?
Nah, this is progress. Why wouldn’t I want to be able to grow my teeth back?
I mean, yes. It’s amazing.
Still weird. I guess I’m stuck on the whole… adults teething issues.
Eh, as long as you don’t get all your teeth knocked out at once, or are old and completely toothless when you get treated, it shouldnt be much of a problem. But yeah, weird thought.
I’ve grown accustomed to liquified chicken gizzards
You do you
Yeah, I’d like to know if they can stop the treatment again. Wouldn’t want to have teeth everywhere.
So, it sounds like the drug basically prevents certain things that normally halt tooth growth- which would be problematic as we’re not constantly loosing teeth.
I will become a shark and you cannot stop me
Honestly, I’m not sure I want to. can I join you instead?
Only because it’s paradigm shifting and worldview shattering.
“Only baby teeth grow back, and if you lose your adult teeth you’re fucked, enjoy your dentures.”
Don’t worry though, you probably have a few decades to realign your worldview. 9/10 of clinical trials fail.
This picture was the first thing that came to mind.
Even worse… what if… get this… hold on a minute… causes…
Vagina Dentata
World’s 1st drug to regrow teeth
Oh!
Vagina dentata
Oh. Uh-oh!
Wow. Queen of Wands, I don’t think I’ve looked at that for over a decade…
This is still better than the alternative. Just ask Methany which she would prefer.
Ive had a couple of teeth removed.
Wonder how this will work… can they regrew 1 tooth in a specific spot?
im sure this won’t end up with manmade horrors beyond my comprehension
have you heard about teratomas? I think that’s exactly what you’re thinking of, except it’s natural
I mean those are weird enough but I’m sure someone’s gonna chug a bottle of whatever this stuff is made of and end up looking like a biblically accurate tooth fairy
Yay reddit humor.
im just doing my part to keep others from relapsing to the bad place
No wonder toddlers are so indestructible. They’re like 90% Teeth.
Don’t Google vagina dentata
But then you miss out on catchy tunes like this
That movie was hilarious.
Oh, hell. Just those two words together made me flinch.
Can we take it… recreationaly?
The grift against the tooth fairy is about to reach fever pitch
Okay, but grow teeth WHERE?
I could be crazy but I swear I’ve heard this a number of times before. It always seemed wonderful as my teeth tend to self-destruct. But nothing ever seems to come from it.
It would be nice if we just naturally grew a new set every 10 years or so but people with strong teeth would be quite annoyed at that especially if they had to do alignment.
Honestly I was hoping crispr would take off more than it actually did come because I’d love to splice myself with the jeans of a shark and just get better teeth every time I lose a tooth
That would be amazing… imagine face planting from a stupid stunt and being like no biggie they’ll grow back. Works for kids and we already know from admittedly gross tumors the human body can grow hair and teeth. Just have to get them in the right place.
Also agree with the other comment to your post… crispr will likely be for the rich. Hell, it probably already is. A cynical view but i don’t sit at that table so who knows.
And they shall call you The Denim Reefer
I am scared if it ever takes off - it will only exist for the rich.
We will soon have a world of CRISPR enhanced humans, and well… me.
Wasn’t crispr designed to be open source to avoid this problem?
My wifes nieces and nephew all had something (DNA? stem cells? Not sure, cant remember) taken by someone in the family who is working on this science to regrow teeth. He doesn’t seem to think its too far off last time i spoke to him.
I didn’t mean to imply it wasn’t possible. I have a relative that works for ITER. And similarly it’s possible but not in my lifetime i imagine.
It might seem silly to relate the 2 but it’s just a feeling… major applicable innovation seems lacking.
Also waiting on sodium-ion or glass batteries as well.
I’ve worked in dental in the past (assistant) and my brother has been sending me these types of articles since I started back in 2004. I always say something like “wild” or “amazing” but really NOTHING ever comes of it so I stopped actually reading what he sends me. It’s just a waste of time.
I’ll believe it when I see it
Thank you for confirming I’m not crazy. At least in that aspect. And also, as someone who has spent an insane amount of hours in that chair thank you for being a DA and dealing with us.
Shit, I need this.
I’m thinking there are going to be very interesting developments in the years to come. So many things that were considered immutable constants about life may change.
