Gary Taubes talks about this in his slew of books about sugar, the historical studies that caused the craze about artificial sweeteners being linked to cancer in the 80’s all were done with massive doses in rats so large that a human being physically could not consume an equivalent dose. I still think it’s worth considering that there is some mechanism at play between these things and cancer, but like you say, the volume is a very important variable.
Gary Taubes talks about this in his slew of books about sugar, the historical studies that caused the craze about artificial sweeteners being linked to cancer in the 80’s all were done with massive doses in rats so large that a human being physically could not consume an equivalent dose. I still think it’s worth considering that there is some mechanism at play between these things and cancer, but like you say, the volume is a very important variable.