I have two machines that back up to a local server using Borg. That whole server in turn backs up to Jottacloud using restic with encryption enabled.
By the way, I wouldn’t use rclone for backups. Use restic or something similar that does incremental backups. Because if you do rclone and then later discover that some files were corrupted locally, then your files are gone. With incremental backups you would still be able to retrieve them.
Oh, or do you mean backing up the stuff that is on the cloud?
I managed to fit an entire Matrix Synapse server on one of those. It works surprisingly well! You will need a domain for it though.